α-Glucosidase inhibitory hydrolyzable tannins from Eugenia jambolana seeds

J Nat Prod. 2012 Aug 24;75(8):1505-9. doi: 10.1021/np300417q. Epub 2012 Aug 6.

Abstract

Three new hydrolyzable tannins including two gallotannins, jamutannins A (1) and B (2), and an ellagitannin, iso-oenothein C (3), along with eight known phenolic compounds were isolated from the seeds of Eugenia jambolana fruit. The structures were elucidated on the basis of spectroscopic data analysis. All compounds isolated were evaluated for α-glucosidase inhibitory effects compared to the clinical drug acarbose.

MeSH terms

  • Glycoside Hydrolase Inhibitors*
  • Hydrolyzable Tannins / chemistry
  • Hydrolyzable Tannins / isolation & purification*
  • Hydrolyzable Tannins / pharmacology*
  • Hypoglycemic Agents
  • India
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plants, Medicinal / chemistry*
  • Seeds / chemistry
  • Syzygium / chemistry*

Substances

  • Glycoside Hydrolase Inhibitors
  • Hydrolyzable Tannins
  • Hypoglycemic Agents
  • iso-oenothein C
  • jamutannin A
  • jamutannin B