Haematobium eggs detection in human bladder cancer and sporocysts in snail vectors: Seven cases report and a review of the Burkina Faso literature

Pathol Biol (Paris). 2012 Oct;60(5):287-90. doi: 10.1016/j.patbio.2011.10.009. Epub 2012 Aug 3.

Abstract

Schistosoma haematobium plays a central role in the development of bladder cancer in Burkina Faso. The objective of this study was to determine the presence of S. haematobium in the bladder cancer and in vector snails. For the first time, formalin-fixed tissues embedded in paraffin were analyzed by immunohistochemistry and PCR. Molecular detection has resulted in 7/7 positive bladder cancer. Finally, as the snail vectors were positive. We suggest the use of molecular methods in the snail vectors for the detection of cysts and in cancerous tissues in larger studies.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Burkina Faso
  • Carcinoma, Squamous Cell / etiology*
  • Carcinoma, Squamous Cell / parasitology*
  • Disease Vectors
  • Eggs
  • Humans
  • Oocysts / pathology*
  • Schistosoma haematobium / genetics
  • Schistosoma haematobium / isolation & purification*
  • Schistosoma haematobium / metabolism
  • Schistosomiasis haematobia / complications*
  • Schistosomiasis haematobia / parasitology
  • Snails / parasitology*
  • Urinary Bladder Neoplasms / etiology*
  • Urinary Bladder Neoplasms / parasitology*