Complete genome sequence of Bacillus cereus NC7401, which produces high levels of the emetic toxin cereulide

Akira Takeno; Akira Okamoto; Keizo Tori; Kenshiro Oshima; Hideki Hirakawa; Hidehiro Toh; Norio Agata; Keiko Yamada; Naotake Ogasawara; Tetsuya Hayashi; Tohru Shimizu; Satoru Kuhara; Masahira Hattori; Michio Ohta

doi:10.1128/JB.01015-12

Complete genome sequence of Bacillus cereus NC7401, which produces high levels of the emetic toxin cereulide

J Bacteriol. 2012 Sep;194(17):4767-8. doi: 10.1128/JB.01015-12.

Authors

Akira Takeno¹, Akira Okamoto, Keizo Tori, Kenshiro Oshima, Hideki Hirakawa, Hidehiro Toh, Norio Agata, Keiko Yamada, Naotake Ogasawara, Tetsuya Hayashi, Tohru Shimizu, Satoru Kuhara, Masahira Hattori, Michio Ohta

Affiliation

¹ Department of Bacteriology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Abstract

We report the complete and annotated genome sequence of Bacillus cereus NC7401, a representative of the strain group that causes emetic-type food poisoning. The emetic toxin, cereulide, is produced by a nonribosomal protein synthesis (NRPS) system that is encoded by a gene cluster on a large resident plasmid, pNCcld.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacillus cereus / genetics*
Bacillus cereus / metabolism*
Bacillus cereus / pathogenicity
Base Sequence
Chromosome Mapping
Depsipeptides / biosynthesis*
Food Microbiology
Foodborne Diseases / microbiology
Genome, Bacterial*
Molecular Sequence Data
Plasmids / genetics
Sequence Analysis, DNA

Substances

Depsipeptides
cereulide

Associated data

GENBANK/AP007209
GENBANK/AP007210
GENBANK/AP007211
GENBANK/AP007212
GENBANK/AP007213
GENBANK/AP007214