In situ effect of dentifrices associated to CO2 laser in the permeability of eroded root dentin

Photomed Laser Surg. 2012 Oct;30(10):573-8. doi: 10.1089/pho.2012.3290. Epub 2012 Aug 13.

Abstract

Objective: The aim of this study was to evaluate, through a crossover 2×2 in situ trial, the effect of a desensitizing dentifrice associated with CO2 laser irradiation to control the permeability of eroded root dentin.

Background data: Facing the increased prevalence of erosive lesion and the need for preventive means to control painful symptoms related to them.

Methods: Eighty slabs of bovine root dentin were subjected to initial erosive challenge (citric acid 0.3%, 2 h), followed by a remineralizing period in artificial saliva (24 h). Specimens were then divided according to dentin treatment: desensitizing dentifrice, desensitizing dentifrice+CO2 laser, fluoride anticavity dentifrice. and fluoride anticavity dentifrice+CO2 laser. After a 2-day lead-in period, 10 volunteers wore an intraoral palatal appliance containing four root dentin slabs, in two phases of 5 days each. During the intraoral phase, one side of the appliance was immersed in 0.3% citric acid, and the opposite side was immersed in deionized water, four times a day. One hour after the immersions, all specimens were brushed with dentifrice slurry provided by the researcher. After a 7-day washout period, volunteers were crossed over on the different dentifrice group. Each phase having been completed, the specimens were evaluated for permeability through an optical microscope.

Results: Data were analyzed using ANOVA and no significant difference (p=0.272) was found between the surface treatments performed on bovine root dentin.

Conclusions: It can be concluded that fluoride anticavity or desensitizing dentifrice, regardless of the association with the CO2 laser irradiation, was able to control the permeability of eroded root dentin.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Cattle
  • Citric Acid / pharmacology
  • Cross-Over Studies
  • Dentifrices / pharmacology*
  • Dentin / drug effects*
  • Dentin / metabolism
  • Dentin / pathology
  • Dentin / radiation effects*
  • Dentin Desensitizing Agents / pharmacology
  • Double-Blind Method
  • Female
  • Humans
  • Lasers, Gas / therapeutic use*
  • Male
  • Middle Aged
  • Permeability
  • Sensitivity and Specificity
  • Sodium Fluoride / pharmacology
  • Tooth Erosion / prevention & control*
  • Tooth Permeability / drug effects*
  • Tooth Permeability / radiation effects*
  • Tooth Root / drug effects
  • Tooth Root / radiation effects
  • Young Adult

Substances

  • Dentifrices
  • Dentin Desensitizing Agents
  • Citric Acid
  • Sodium Fluoride