The transcription factor c-Maf in sensory neuron development

Transcription. 2012 Nov-Dec;3(6):285-9. doi: 10.4161/trns.21809. Epub 2012 Aug 14.

Abstract

The proto-oncogene c-Maf has been shown to be an important transcriptional regulator in the differentiation of a number of cellular contexts, like the eye and hematopoietic system. Here we discuss the recent progress made in understanding c-Maf function in the nervous system.

Keywords: Ret; c-Maf; development; mechanoreceptors; pacinian corpuscles; sensory neuron; skin innervation; touch.

MeSH terms

  • Animals
  • Humans
  • Mechanoreceptors / physiology
  • Proto-Oncogene Mas
  • Proto-Oncogene Proteins c-maf / physiology*
  • Sensory Receptor Cells / physiology*
  • Skin Physiological Phenomena
  • Vibration

Substances

  • MAS1 protein, human
  • Proto-Oncogene Mas
  • Proto-Oncogene Proteins c-maf