How a mismatch repair enzyme balances the needs for efficient lesion processing and minimal action on undamaged DNA

Cell Cycle. 2012 Sep 15;11(18):3345-6. doi: 10.4161/cc.21843. Epub 2012 Aug 23.

Abstract

Comment on: Maiti A, et al. Proc Natl Acad Sci USA 2012; 109:8091-6.

Publication types

  • Editorial

MeSH terms

  • Biocatalysis
  • Catalytic Domain
  • Conserved Sequence
  • CpG Islands
  • DNA / metabolism
  • DNA Damage*
  • DNA Mismatch Repair*
  • Humans
  • Mutation / genetics
  • Thymine DNA Glycosylase / chemistry
  • Thymine DNA Glycosylase / genetics
  • Thymine DNA Glycosylase / metabolism*

Substances

  • DNA
  • Thymine DNA Glycosylase