[Deciphering functional activity of TLX homeodomain oncogenes in T-ALL: a clue for a differentiating therapy?]

MeSH terms

• Atrophy
• Cell Survival
• Gene Expression Regulation, Leukemic
• Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor / drug effects
• Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor / genetics
• Genes, Homeobox*
• Homeodomain Proteins / genetics
• Homeodomain Proteins / physiology*
• Humans
• Lymphopoiesis / drug effects
• Lymphopoiesis / genetics*
• Molecular Targeted Therapy
• Neoplasm Proteins / genetics
• Neoplasm Proteins / physiology*
• Oncogenes*
• Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
• Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics*
• Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / pathology
• Proto-Oncogene Protein c-ets-1 / physiology
• Proto-Oncogene Proteins / genetics
• Proto-Oncogene Proteins / physiology*
• Receptors, Antigen, T-Cell, alpha-beta / biosynthesis
• Receptors, Antigen, T-Cell, alpha-beta / genetics
• Thymocytes / drug effects
• Thymocytes / pathology*
• Thymus Gland / pathology