The proportion of CD34(+)CD38(low or neg) myeloblasts, but not side population frequency, predicts initial response to induction therapy in patients with newly diagnosed acute myeloid leukemia

Leukemia. 2013 Mar;27(3):728-31. doi: 10.1038/leu.2012.217. Epub 2012 Jul 31.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • ADP-ribosyl Cyclase 1 / metabolism*
  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Antigens, CD34 / metabolism*
  • Blast Crisis / diagnosis
  • Blast Crisis / genetics
  • Blast Crisis / therapy*
  • Case-Control Studies
  • Combined Modality Therapy
  • Cytogenetic Analysis
  • Female
  • Flow Cytometry
  • Granulocyte Precursor Cells / metabolism
  • Granulocyte Precursor Cells / pathology*
  • Humans
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / genetics
  • Leukemia, Myeloid, Acute / therapy*
  • Male
  • Mice
  • Mice, Inbred NOD
  • Mice, SCID
  • Middle Aged
  • Prognosis
  • Receptors, Interleukin-2 / physiology
  • Remission Induction
  • Young Adult

Substances

  • Antigens, CD34
  • Receptors, Interleukin-2
  • ADP-ribosyl Cyclase 1