Abstract
The stem and stem bark of Polyalthia longifolia afforded the cytotoxic aporphine alkaloid liriodenine [1], as well as two aporphine alkaloids, noroliveroline [2] and oliveroline-beta-N-oxide [3] and three azafluorene alkaloids, darienine [4], polyfothine [6], and isooncodine [7], which are not bioactive. Polyfothine [6] and isooncodine [7] are new natural compounds.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / isolation & purification*
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Alkaloids / pharmacology
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Aporphines / chemistry
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Aporphines / isolation & purification
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Aporphines / pharmacology*
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Drug Screening Assays, Antitumor
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Plants / analysis*
Substances
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Alkaloids
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Antineoplastic Agents, Phytogenic
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Aporphines
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polyfothine
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darienine
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isooncodine
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liriodenine