Lymph node metastasis between sternocleidomastoid and sternohyoid muscle in clinically node-positive papillary thyroid carcinoma

Head Neck. 2013 Aug;35(8):1168-70. doi: 10.1002/hed.23099. Epub 2012 Aug 28.

Abstract

Background: There have been few reports on lymph node metastasis between sternocleidomastoid and sternohyoid muscle (originally LNSS) in clinically node positive (cN+) papillary thyroid carcinoma (PTC). Therefore, our objective was to investigate the significance of LNSS metastasis.

Methods: A total of 115 patients with cN+ PTC underwent a neck dissection with LNSS, as a separate pathologic specimen to be analyzed for the correlation between LNSS and sex, age, tumor size, tumor site, initial or reoperative treatment, lateral cervical lymph nodes, and central compartment metastasis.

Results: The positive rate of LNSS was 22.6%. LNSS metastasis was correlated with a primary site in the inferior pole, the lateral nodal metastasis, level III and level IV nodal metastasis, but not with other clinical parameters.

Conclusion: In cN+ PTC, especially a primary site in the inferior pole, level III and/or level IV metastasis, attention should be given to excising the nodal tissue in LNSS.

Keywords: cervical lymph node metastasis; lymph node between sternocleidomastoid and sternohyoid muscles; neck dissection; papillary thyroid carcinoma; therapy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Carcinoma / pathology*
  • Carcinoma / surgery*
  • Carcinoma, Papillary
  • Female
  • Humans
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Muscle Neoplasms / secondary*
  • Muscle Neoplasms / surgery*
  • Neck Dissection*
  • Neck Muscles / pathology*
  • Retrospective Studies
  • Sex Factors
  • Thyroid Cancer, Papillary
  • Thyroid Neoplasms / pathology*
  • Thyroid Neoplasms / surgery*
  • Tumor Burden