Gastrointestinal perforations in neonatal period: experience over 10 years

Pediatr Emerg Care. 2012 Sep;28(9):886-8. doi: 10.1097/PEC.0b013e31826beb0c.

Abstract

Aim: This report describes our experience concerning gastrointestinal perforation due to necrotizing enterocolitis during a 10-year period.

Method: The cases of 27 gastrointestinal perforations, which were treated in our hospital, were retrospectively reviewed.

Results: All patients were neonates and infants up to the age of 2 months. The study population consisted of 16 boys (59.3%) and 11 girls (40.7%). Twenty-one neonates (77.8%) were preterm, and the median gestational age was 28 weeks. Twenty-four cases (88.9%) of perforation underwent laparotomy. The overall mortality was 63%. Seventy-six percent of the preterm neonates and only 16.7% of the full-term neonates died.

Conclusions: Gastrointestinal perforation is still connected with a high mortality rate, with necrotizing enterocolitis being the main cause of death. The neonates who did not undergo surgery all died.

MeSH terms

  • Cause of Death
  • Female
  • Gestational Age
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature
  • Intestinal Perforation / mortality*
  • Intestinal Perforation / surgery*
  • Laparotomy
  • Male
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome