Filaggrin degradation by caspase-14 is required for UVB photoprotection but does not influence allergic sensitization in a mouse model of atopic dermatitis

J Invest Dermatol. 2012 Dec;132(12):2857-60. doi: 10.1038/jid.2012.236. Epub 2012 Aug 30.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Caspases / metabolism*
  • Dermatitis, Atopic / immunology
  • Dermatitis, Atopic / metabolism*
  • Dermatitis, Atopic / pathology
  • Disease Models, Animal
  • Filaggrin Proteins
  • Hypersensitivity / immunology
  • Hypersensitivity / metabolism*
  • Intermediate Filament Proteins / metabolism*
  • Mice
  • Skin / immunology
  • Skin / metabolism*
  • Skin / radiation effects
  • Ultraviolet Rays / adverse effects

Substances

  • Filaggrin Proteins
  • Intermediate Filament Proteins
  • Casp14 protein, mouse
  • Caspases