The carbapenem-resistant Enterobacteriaceae score: a bedside score to rule out infection with carbapenem-resistant Enterobacteriaceae among hospitalized patients

Am J Infect Control. 2013 Feb;41(2):180-2. doi: 10.1016/j.ajic.2012.02.036. Epub 2012 Aug 30.

Abstract

Patients infected with carbapenem-resistant Enterobacteriaceae often experience delays in initiation of appropriate antimicrobial therapy and increased mortality. A score was developed to differentiate bloodstream infections caused by carbapenem-resistant Enterobacteriaceae (16 patients) versus extended-spectrum β-lactamase-producing Enterobacteriaceae (166 patients). A score of ≥ 32 demonstrated high area under the curve of 0.80 (95% confidence interval: 0.68-0.92) and a negative predictive value of 97%.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Bacteremia / drug therapy
  • Bacteremia / microbiology*
  • Bacteremia / pathology
  • Carbapenems / pharmacology*
  • Cohort Studies
  • Decision Support Techniques*
  • Enterobacteriaceae / drug effects*
  • Enterobacteriaceae Infections / drug therapy
  • Enterobacteriaceae Infections / microbiology*
  • Enterobacteriaceae Infections / pathology
  • Humans
  • Predictive Value of Tests
  • beta-Lactam Resistance*

Substances

  • Carbapenems