Late follow-up of saphenofemoral junction ligation combined with ultrasound-guided foam sclerotherapy in patients with venous ulcers

Ann Vasc Surg. 2012 Oct;26(7):977-81. doi: 10.1016/j.avsg.2012.03.013.

Abstract

Background: Venous ulcers are a frequent complication of venous disease, and a variety of healing methods have been proposed for these lesions. The objective of this study was to provide late follow-up data for a group of patients with venous ulcers who presented with advanced chronic venous insufficiency and were treated with saphenofemoral junction ligation combined with ultrasound-guided foam sclerotherapy.

Methods: This was a prospective study of 35 patients. Patients were classified as CEAP6 and were followed during a 45- to 68-month period. The following variables were assessed: wound healing, ultrasound findings, and venous clinical severity scores.

Results: The following ultrasound findings were observed: total and partial recanalization in 19 patients (treatment failure) and occlusion in 13 patients (treatment success). Two patients were lost to follow-up, and one patient died. Ulcers healed between 30 and 70 days and remained closed for a mean period of 48 months (Kaplan-Meyer method). The analysis of clinical severity scores (pain, edema, pigmentation, lipodermatosclerosis, and inflammation) revealed significant improvement when comparing pre- and post-treatment results.

Conclusion: Our preliminary findings suggest that saphenofemoral junction ligation combined with ultrasound-guided foam sclerotherapy is a feasible and simple palliative treatment method for this group of patients.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Chronic Disease
  • Female
  • Femoral Vein / diagnostic imaging
  • Femoral Vein / surgery*
  • Follow-Up Studies
  • Humans
  • Kaplan-Meier Estimate
  • Ligation
  • Male
  • Middle Aged
  • Palliative Care
  • Prospective Studies
  • Saphenous Vein / diagnostic imaging
  • Saphenous Vein / surgery*
  • Sclerosing Solutions / administration & dosage*
  • Sclerosing Solutions / adverse effects
  • Sclerotherapy* / adverse effects
  • Severity of Illness Index
  • Time Factors
  • Treatment Outcome
  • Ultrasonography, Interventional*
  • Varicose Ulcer / diagnostic imaging
  • Varicose Ulcer / etiology
  • Varicose Ulcer / surgery
  • Varicose Ulcer / therapy*
  • Vascular Surgical Procedures* / adverse effects
  • Venous Insufficiency / complications
  • Venous Insufficiency / diagnostic imaging
  • Venous Insufficiency / surgery
  • Venous Insufficiency / therapy*
  • Wound Healing

Substances

  • Sclerosing Solutions