Abstract
An excellent biosensor with ZnO nanowires-gated AlGaAs/GaAs high electron mobility transistor (HEMT) was used to detect lactic acid. Due to the new structure, addition of the Si-doped GaAs cap layer, the HEMT biosensor could detect a wide range of lactic acid concentrations from 0.03 nM to 300 mM. The novel biosensor exhibiting good performance along with fast response, high sensitivity, wide detection range, and long-term stability, can be integrated with a commercially available transmitter to realize lactic acid detection.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aluminum / chemistry*
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Arsenicals / chemistry*
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Biosensing Techniques / instrumentation*
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Biosensing Techniques / methods
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Enzymes, Immobilized / chemistry*
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Enzymes, Immobilized / metabolism
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Gallium / chemistry*
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Lactic Acid / analysis*
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Lactic Acid / metabolism
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Limit of Detection
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Mixed Function Oxygenases / chemistry
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Mixed Function Oxygenases / metabolism
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Nanowires / chemistry*
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Zinc Oxide / chemistry*
Substances
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Arsenicals
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Enzymes, Immobilized
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gallium arsenide
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Lactic Acid
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Gallium
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Aluminum
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Mixed Function Oxygenases
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lactate 2-monooxygenase
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Zinc Oxide