Abstract
A new case of Reynold's syndrome is reported. This patient was a 70 years old woman with scleroderma (grade II) and PBC (grade III - IV), associated with Sjögren's syndrome and cryoglobulinemia. She experienced 10 years earlier Raynaud's syndrome and arthralgia. A review of the Literature reveals 22 other detailed cases whose data are collected in this study. Considerations upon a common pathophysiology for scleroderma, PBC and Sjögren's syndrome are developed. Impairment of the function of suppressor T cells in patients undergoing these diseases is possible.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Aged
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Autoantibodies / analysis
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Cryoglobulins / analysis
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Female
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Humans
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Immunoglobulin G / analysis
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Immunoglobulin M / analysis
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Joint Diseases / etiology
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Liver Cirrhosis, Biliary / immunology*
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Liver Cirrhosis, Biliary / pathology
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Middle Aged
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Raynaud Disease / etiology
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Scleroderma, Systemic / immunology*
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Scleroderma, Systemic / pathology
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Sjogren's Syndrome / complications
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Sjogren's Syndrome / immunology
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Syndrome
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T-Lymphocytes / immunology
Substances
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Autoantibodies
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Cryoglobulins
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Immunoglobulin G
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Immunoglobulin M