Intrahepatic transplantation of cord blood CD34+ cells into newborn NOD/SCID-IL2Rγ(null) mice allows efficient multi-organ and multi-lineage hematopoietic engraftment without accessory cells

Clin Immunol. 2012 Nov;145(2):89-91. doi: 10.1016/j.clim.2012.08.001. Epub 2012 Aug 11.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • Antigen-Presenting Cells / cytology
  • Antigen-Presenting Cells / radiation effects
  • Antigen-Presenting Cells / transplantation
  • Antigens, CD34 / immunology
  • Cell Lineage
  • Cord Blood Stem Cell Transplantation
  • Fetal Blood / cytology
  • Fetal Blood / immunology
  • Fetal Blood / transplantation*
  • Gamma Rays
  • Graft Survival*
  • Humans
  • Interleukin Receptor Common gamma Subunit / deficiency*
  • Interleukin Receptor Common gamma Subunit / genetics
  • Interleukin Receptor Common gamma Subunit / immunology
  • Liver / cytology
  • Liver / immunology*
  • Mice
  • Mice, Inbred NOD
  • Mice, SCID
  • Transplantation Tolerance
  • Transplantation, Heterologous

Substances

  • Antigens, CD34
  • Il2rg protein, mouse
  • Interleukin Receptor Common gamma Subunit