Chicken dendritic cells and type II pneumocytes express a common intracellular epitope

Br Poult Sci. 2012;53(3):397-400. doi: 10.1080/00071668.2012.703775.

Abstract

1. CVI-ChNL 74·3, a dendritic cell-specific monoclonal antibody (mAb) also identifies chicken lung granular pneumocytes (type II pneumocytes), which produce surfactant. 2. The 74·3 mAb does not cross-react with any other avian or mammalian granular pneumocyte, and provides a convenient tool for monitoring the status of type II pneumocytes in the chicken lung.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alveolar Epithelial Cells / immunology
  • Alveolar Epithelial Cells / metabolism*
  • Animals
  • Antibodies, Monoclonal / immunology
  • Antibodies, Monoclonal / metabolism*
  • Chickens / immunology*
  • Chickens / metabolism*
  • Dendritic Cells, Follicular / immunology
  • Dendritic Cells, Follicular / metabolism*
  • Epitopes / immunology
  • Epitopes / metabolism*
  • Lung / immunology
  • Lung / metabolism
  • Surface-Active Agents / metabolism

Substances

  • Antibodies, Monoclonal
  • Epitopes
  • Surface-Active Agents