Efficacy of intradermal radiofrequency combined with autologous platelet-rich plasma in striae distensae: a pilot study

Int J Dermatol. 2012 Oct;51(10):1253-8. doi: 10.1111/j.1365-4632.2012.05530.x.

Abstract

Background: Different types of laser have recently been reported as effective tools of treatment in striae distensae. Although fractional photothermolysis is effective for striae distensae, post-inflammatory hyperpigmentation is a major concern and common complication. There are no reports of the effects of using an intradermal radiofrequency (RF) device in striae distensae. Autologous platelet-rich plasma (PRP) is an effective treatment known for its wound-healing effects.

Methods: Nineteen Asian female patients with striae distensae were enrolled in this study. Three sessions of intradermal RF (1134-kHz frequency, 12-W power, 26-G electrode size) combined with autologous PRP were performed in each patient at intervals of four weeks. Patients were evaluated subjectively by the investigators and by themselves.

Results: Evaluation of clinical results at four weeks after treatment showed that only one (5.3%) of the 19 patients achieved excellent improvement, whereas seven (36.8%) demonstrated marked improvement, six (31.6%) showed moderate improvement, and five (26.3%) showed mild improvement. None of the patients showed worsening of striae distensae. A total of 63.2% of patients reported they were "satisfied" or "very satisfied" with the degree of overall improvement.

Conclusions: Intradermal RF combined with autologous PRP appears to be an effective treatment for striae distensae.

MeSH terms

  • Adult
  • Female
  • Humans
  • Patient Satisfaction
  • Pilot Projects
  • Platelet-Rich Plasma*
  • Radiofrequency Therapy*
  • Striae Distensae / radiotherapy
  • Striae Distensae / therapy*
  • Treatment Outcome
  • Young Adult