The non-casual relation between eosinophilia and thrombotic microangiopathy

Transfus Apher Sci. 2012 Dec;47(3):365-7. doi: 10.1016/j.transci.2012.07.021. Epub 2012 Sep 17.

Abstract

There are only a few cases in the literature that describes the association between hypereosinophilic syndromes and thrombotic microangiopathy (TMA). Here we present the case of a man who suddenly developed a TMA in the context of eosinophilic pneumonia, who recovered successfully with six sessions of plasmapheresis and corticoids. Although the Pathophysiology is unknown, we hypothesize about the prothrombotic effects of the eosinophils. Also we describe a literature review.

Publication types

  • Case Reports

MeSH terms

  • Eosinophilia / complications*
  • Eosinophilia / therapy
  • Humans
  • Male
  • Middle Aged
  • Pulmonary Eosinophilia / blood
  • Pulmonary Eosinophilia / therapy
  • Thrombotic Microangiopathies / complications*
  • Thrombotic Microangiopathies / therapy