Glycemic variability and glycemic control in the acutely ill cardiac patient

Heart Fail Clin. 2012 Oct;8(4):523-38. doi: 10.1016/j.hfc.2012.06.006. Epub 2012 Aug 9.

Abstract

The mechanisms for hyperglycemia-mediated harm in the hospitalized cardiac patient are poorly understood. Potential obstacles in the inpatient management of hyperglycemia in cardiac patients include rapidly changing clinical status, frequent procedures and interruptions in carbohydrate exposure, and short hospital length of stay. A patient's preadmission regimen is rarely suitable for inpatient glycemic control. Instead, an approach to a flexible, physiologic insulin regimen is described, which is intended to minimize glycemic excursions. When diabetes or hyperglycemia is addressed early and consistently, the hospital stay can serve as a potential window of opportunity for reinforcing self-care behaviors that reduce long-term complications.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Blood Glucose / metabolism
  • Cardiovascular Diseases / metabolism*
  • Cardiovascular Diseases / pathology
  • Diabetes Mellitus / metabolism*
  • Diabetes Mellitus / pathology
  • Diabetes Mellitus / prevention & control
  • Glucagon-Like Peptide 1
  • Humans
  • Hyperglycemia / metabolism*
  • Hyperglycemia / pathology
  • Hyperglycemia / prevention & control
  • Insulin / administration & dosage
  • Insulin / therapeutic use
  • Risk

Substances

  • Blood Glucose
  • Insulin
  • Glucagon-Like Peptide 1