Diagnostic tools of metabolic and structural brain disturbances in neonatal non-ketotic hyperglycinemia

Pediatr Int. 2012 Oct;54(5):717-20. doi: 10.1111/j.1442-200X.2012.03591.x.

Abstract

Non-ketotic hyperglycinemia (NKH) is a rare autosomal recessive disorder of glycine metabolism. We report a newborn case of NKH and discuss the effects of this rare disease on brain metabolism and structure together with amplitude-integrated electroencephalography, cranial magnetic resonance and magnetic resonance spectroscopy findings which are very rarely reported together so far.

Publication types

  • Case Reports

MeSH terms

  • Brain / metabolism*
  • Brain / pathology
  • Electroencephalography
  • Female
  • Humans
  • Hyperglycinemia, Nonketotic / diagnosis*
  • Hyperglycinemia, Nonketotic / pathology
  • Infant, Newborn
  • Magnetic Resonance Spectroscopy