Prospective multicenter study of Pneumocystis jirovecii colonization among cystic fibrosis patients in France

J Clin Microbiol. 2012 Dec;50(12):4107-10. doi: 10.1128/JCM.01974-12. Epub 2012 Sep 26.

Abstract

Pneumocystis carriage was detected in 12.5% of 104 cystic fibrosis (CF) patients during a prospective multicenter French study, with a prevalence of genotype 85C/248C and geographic variations. It was significantly associated with the absence of Pseudomonas aeruginosa colonization and a greater forced expiratory volume in 1 s. Results are discussed considering the natural history of CF.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Carrier State / epidemiology*
  • Carrier State / microbiology
  • Cystic Fibrosis / complications*
  • Female
  • France / epidemiology
  • Genotype
  • Humans
  • Male
  • Molecular Typing
  • Mycological Typing Techniques
  • Pneumocystis Infections / epidemiology*
  • Pneumocystis Infections / microbiology
  • Pneumocystis carinii / classification
  • Pneumocystis carinii / genetics
  • Pneumocystis carinii / isolation & purification*
  • Prospective Studies
  • Young Adult