Effects of a pulsed light-induced stress on Enterococcus faecalis

J Appl Microbiol. 2013 Jan;114(1):186-95. doi: 10.1111/jam.12029. Epub 2012 Oct 30.

Abstract

Aims: Pulsed light (PL) technology is a surface decontamination process that can be used on food, packaging or water. PL efficiency may be limited by its low degree of penetration or because of a shadow effect. In these cases, surviving bacteria will be able to perceive PL as a stress. Such a stress was mimicked using low transmitted energy conditions, and its effects were investigated on the highly environmental adaptable bacterium Enterococcus faecalis V583.

Methods and results: In these laboratory conditions, a complete decontamination of the artificially inoculated medium was performed using energy doses as low as 1.8 J cm(-2) , while a treatment of 0.5, 1 and 1.2 J cm(-2) led to a 2.2, 6 and 7-log(10) CFU ml(-1) reduction in the initial bacterial population, respectively. Application of a 0.5 J cm(-2) pretreatment allowed the bacteria to resist more efficiently a 1.2 J cm(-2) subsequent PL dose. This 0.5 J cm(-2) treatment increased the bacterial mutation frequency and affected the abundance of 19 proteins as revealed by a global proteome analysis.

Conclusions: Enterococcus faecalis is able to adapt to a PL treatment, providing a molecular response to low-energy PL dose, leading to enhanced resistance to a subsequent treatment and increasing the mutation frequency.

Significance and impact of the study: This study gives further insights on Ent. faecalis capacities to adapt and to resist to stress.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological
  • Bacterial Proteins / genetics
  • Decontamination / methods*
  • Enterococcus faecalis / genetics
  • Enterococcus faecalis / radiation effects*
  • Light*
  • Microbial Viability
  • Mutation Rate
  • Proteome / analysis
  • Stress, Physiological

Substances

  • Bacterial Proteins
  • Proteome