Lyme endocarditis

Clin Microbiol Infect. 2012 Dec;18(12):E531-2. doi: 10.1111/1469-0691.12016. Epub 2012 Oct 9.

Abstract

Lyme borreliosis is a common tick-borne disease with a wide variety of clinical manifestations. Cardiac involvement has been reported during both the acute phase (atrioventricular block, pericarditis) and the chronic stage (dilated cardiomyopathy), but is rare (<5%). Here we describe the first case of Borrelia afzelii Lyme endocarditis, in a 61-year-old man living in an endemic area of France. The diagnosis was confirmed by detection of B. afzelii DNA in the mitral valve by specific real-time PCR. He was treated empirically with amoxicillin for 6 weeks and remains well 12 months later.

Publication types

  • Case Reports

MeSH terms

  • Amoxicillin / administration & dosage
  • Anti-Bacterial Agents / administration & dosage
  • Borrelia burgdorferi Group / isolation & purification*
  • DNA, Bacterial / genetics
  • DNA, Bacterial / isolation & purification
  • Endocarditis, Bacterial / diagnosis*
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / microbiology*
  • France
  • Humans
  • Lyme Disease / complications*
  • Lyme Disease / diagnosis*
  • Lyme Disease / drug therapy
  • Lyme Disease / microbiology
  • Male
  • Middle Aged
  • Mitral Valve / microbiology
  • Real-Time Polymerase Chain Reaction
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • Amoxicillin