Abstract
The effects of a long-acting somatostatin analog SMS 201-995 injections on the basal and angiotensin II-stimulated [3H]-thymidine uptake by the rat adrenal glands incubated in vitro were examined. It was shown that SMS 201-995 significantly inhibited the [3H]-thymidine uptake and, additionally, suppressed the stimulatory effect of a single angiotensin II injection.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adrenal Glands / drug effects
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Adrenal Glands / metabolism*
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Angiotensin II / antagonists & inhibitors
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Angiotensin II / pharmacology*
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Animals
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DNA Replication / drug effects*
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Kinetics
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Male
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Octreotide / pharmacology*
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Rats
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Rats, Inbred Strains
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Reference Values
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Thymidine / metabolism*
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Tritium
Substances
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Tritium
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Angiotensin II
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Octreotide
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Thymidine