Abstract
The response of S. pombe, also known as fission yeast, to misfolded proteins involves mechanisms that have not been observed in other species.
Keywords:
Bip1 mRNA stabilization; ER homeostasis; Ire1; Unfolded Protein Response; selective mRNA decay.
MeSH terms
-
3' Untranslated Regions
-
Endoplasmic Reticulum / metabolism
-
Fungal Proteins / genetics*
-
Fungal Proteins / metabolism
-
Gene Expression Regulation, Fungal*
-
HSP70 Heat-Shock Proteins / genetics*
-
HSP70 Heat-Shock Proteins / metabolism
-
Homeostasis / genetics
-
Protein Biosynthesis
-
Protein Folding
-
Protein Serine-Threonine Kinases / genetics*
-
Protein Serine-Threonine Kinases / metabolism
-
RNA Splicing
-
RNA Stability
-
RNA, Messenger / genetics*
-
RNA, Messenger / metabolism
-
Schizosaccharomyces / genetics*
-
Schizosaccharomyces / metabolism
-
Signal Transduction
-
Transcription, Genetic
-
Unfolded Protein Response*
Substances
-
3' Untranslated Regions
-
Fungal Proteins
-
HSP70 Heat-Shock Proteins
-
KAR2 protein, yeast
-
RNA, Messenger
-
Protein Serine-Threonine Kinases