Description of "yaaf", the vesicular fever caused by acute Rickettsia felis infection in Senegal

J Infect. 2013 Jun;66(6):536-40. doi: 10.1016/j.jinf.2012.10.005. Epub 2012 Oct 13.

Abstract

Rickettsiosis caused by Rickettsia felis is an emerging infection in Africa and may account for 3-4% of ambulatory febrile fevers. We report herein a case of R. felis infection, for which we propose the name "yaaf", meaning vesicle, in an 8-month-old girl who was diagnosed in the field by real-time PCR analysis of a skin lesion; these PCR analysis was performed at a local experimental point-of-care laboratory. The clinical presentation was polymorphous skin lesions, including papules, vesicles, erosions and ulcers. The patient did not produce antibodies against Rickettsia. We suggest that this disease may be a primary infection caused by R. felis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Female
  • Humans
  • Infant
  • Rickettsia Infections / microbiology*
  • Rickettsia felis / isolation & purification*
  • Senegal
  • Skin / microbiology
  • Skin / pathology
  • Skin Diseases, Bacterial / microbiology*