Abstract
Semiconducting and metallic single-walled carbon nanotubes (s-SWNTs and m-SWNTs) were enriched by agarose gel chromatography and their photothermal and photodynamic effects were compared in H(2)O. Under near-infrared laser irradiation, s-SWNTs generated reactive oxygen species (ROS) more than m-SWNTs, whereas m-SWNTs produced heat more efficiently than s-SWNTs. More importantly, cancer cell killing by PDE of s-SWNTs has been disclosed for the first time.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology*
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Cell Line, Tumor
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Cell Survival / drug effects
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Dose-Response Relationship, Drug
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Drug Screening Assays, Antitumor
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Humans
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Nanotubes, Carbon / chemistry*
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Photosensitizing Agents / chemistry
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Photosensitizing Agents / pharmacology*
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Reactive Oxygen Species / metabolism
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Semiconductors
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Structure-Activity Relationship
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Temperature*
Substances
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Antineoplastic Agents
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Nanotubes, Carbon
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Photosensitizing Agents
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Reactive Oxygen Species