Clopidogrel-induced spontaneous pectoral hematoma

Indian J Pharmacol. 2012 Jul-Aug;44(4):526-7. doi: 10.4103/0253-7613.99342.

Abstract

Clopidogrel is an oral antiplatelet agent used in the treatment of coronary artery disease, peripheral vascular disease and cerebrovascular disease. Gastrointestinal symptoms including nausea, diarrhea and constipation are the common side effects of this drug. Serious side effects like intracranial hemorrhage and severe neutropenia were also reported but spontaneous pectoral hematoma due to the clopidogrel has not been reported previously. We present a case of large spontaneous pectoral hematoma during clopidogrel therapy in an elderly woman.

Keywords: Clopidogrel; adverse effect; pectoral hematoma.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Clopidogrel
  • Female
  • Hematoma / chemically induced*
  • Hematoma / diagnosis*
  • Humans
  • Pectoralis Muscles / drug effects*
  • Pectoralis Muscles / pathology*
  • Platelet Aggregation Inhibitors / adverse effects
  • Ticlopidine / adverse effects
  • Ticlopidine / analogs & derivatives*

Substances

  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Ticlopidine