Two new anthraquinone dimers from the fruit bodies of Bulgaria inquinans

Ning Li; Jing Xu; Xian Li; Peng Zhang

doi:10.1016/j.fitote.2012.10.006

Two new anthraquinone dimers from the fruit bodies of Bulgaria inquinans

Fitoterapia. 2013 Jan:84:85-8. doi: 10.1016/j.fitote.2012.10.006. Epub 2012 Oct 23.

Authors

Ning Li¹, Jing Xu, Xian Li, Peng Zhang

Affiliation

¹ School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.

PMID: 23098878
DOI: 10.1016/j.fitote.2012.10.006

Abstract

Two new dimeric anthraquinone derivatives, bulgareone A(1) and bulgareone B(2), were isolated from the fruit bodies of Bulgaria inquinans. Their structures were elucidated on the basis of extensive spectroscopic analysis. The in vitro cytotoxic activity of compounds 1 and 2 was assayed. They displayed inhibitive activities against human cancer cell lines HL60 and K562.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anthraquinones / chemistry
Anthraquinones / pharmacology*
Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology*
Ascomycota / chemistry*
Cell Line, Tumor
Fruiting Bodies, Fungal / chemistry*
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
Leukemia, Myeloid, Acute / drug therapy
Molecular Structure

Substances

Anthraquinones
Antineoplastic Agents
bulgareone A
bulgareone B