Structure by sequencing: discovery of hidden messages in the noncoding RNA fraction

Alessandro Bonetti; Piero Carninci

doi:10.1016/j.molcel.2012.10.004

Structure by sequencing: discovery of hidden messages in the noncoding RNA fraction

Mol Cell. 2012 Oct 26;48(2):153-5. doi: 10.1016/j.molcel.2012.10.004.

Authors

Alessandro Bonetti¹, Piero Carninci

Affiliation

¹ Omics Science Center, RIKEN Yokohama Institute, Yokohama City, Kanagawa 230-0045, Japan.

PMID: 23102264
DOI: 10.1016/j.molcel.2012.10.004

Abstract

A lack of tools has hampered the search for the potential functions of the abundant noncoding RNA (ncRNA) portion of the genome. Wan et al. (2012) report a new sequencing-based method for determining ncRNA secondary structure termed PARTE, promising to accelerate ncRNA studies.

Publication types

Comment

MeSH terms

Genome
Nucleic Acid Conformation*
RNA Folding
RNA, Untranslated / chemistry
RNA, Untranslated / genetics*
Transcriptome / genetics

Substances

RNA, Untranslated