Acute ST-elevation inferior myocardial infarction in a patient with a non-obstructive mechanical mitral valve thrombosis

Cardiovasc J Afr. 2012 Oct 23;23(9):e7-8. doi: 10.5830/CVJA-2012-047.

Abstract

The risk of systemic embolisation in patients with prosthetic heart valves who are receiving anticoagulation therapy is 0.5 to 1.7% per patient year and most cases present with cerebrovascular events. Here we report the case of a 42-year-old woman who was uneventfully treated with a low dose, prolonged infusion of tissue plasminogen activator because of non-obstructive prosthetic mitral valve thrombosis. It presented as coronary embolism and resulted in acute ST-elevation inferior myocardial infarction.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Coronary Angiography
  • Coronary Thrombosis / chemically induced
  • Coronary Thrombosis / diagnosis*
  • Coronary Thrombosis / physiopathology
  • Drug Dosage Calculations
  • Echocardiography, Transesophageal
  • Electrocardiography
  • Female
  • Heart Valve Prosthesis Implantation*
  • Humans
  • Mitral Valve / diagnostic imaging
  • Mitral Valve / surgery
  • Mitral Valve Annuloplasty*
  • Myocardial Infarction / chemically induced
  • Myocardial Infarction / diagnosis*
  • Myocardial Infarction / physiopathology
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / physiopathology
  • Tissue Plasminogen Activator / administration & dosage
  • Tissue Plasminogen Activator / adverse effects*

Substances

  • Tissue Plasminogen Activator