We presented a rare surgical case of recurrent multiple left atrial myxomas, who had a history of surgery for multiple left ventricular myxomas 28 years ago. The case was a 42-year-old female. She developed dyspnea, cough, and palpitation due to functional mitral valve obstruction by myxoma. There were a 30 mm large pedunculated tumor on the left atrial septum and 2 small tumors near the orifice of the right upper pulmonary vein. These tumors were excised with the left atrial endothelium and the defect was reconstructed with a bovine pericardium.