Abstract
New trisdipicolinic acid-lanthanide complexes are reported as phasing agents for X-ray crystallography of proteins. It is demonstrated that CuAAC modifications allow protein co-crystallization with low concentration of lanthanide complexes leading to an accurate structure determination.
MeSH terms
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Crystallography, X-Ray
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Europium / chemistry*
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Models, Molecular
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Molecular Structure
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Muramidase / chemistry*
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Muramidase / metabolism
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Organometallic Compounds / chemical synthesis
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Organometallic Compounds / chemistry*
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Picolinic Acids / chemistry*
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Plant Proteins / chemistry*
Substances
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Organometallic Compounds
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Picolinic Acids
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Plant Proteins
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Europium
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thaumatin protein, plant
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hen egg lysozyme
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Muramidase