My recollections of the development of clinical cytology at Merkur University Hospital cover a 30-year period, from 1955 to 1985, and succession of generations. The beginning is always exciting, pervaded by youthful enthusiasm, while memories are quite nostalgic. That is how I also felt at the "Ruzdić's" medical biochemistry laboratory. The founders of clinical cytology at Merkur University Hospital were the clinicians Erik Hauptmann (hematologist), Zdenko Skrabalo (endocrinologist) and Zvonimir Singer (gynecologist, cytogeneticist), with great contribution by Ibrahim Ruzdić (biochemist). As the first head of cytology laboratory at University Department of Medicine, I realized what was crucial for such a successful development of clinical cytology at our Hospital; it was so because new technologies were continuously introduced in agreement with clinicians, along with the basic routine cytodiagnosis, while paying special attention to staff education (postgraduate study in clinical cytology since 1967; residency in cytology since 1974; education of cytotechnologists since 1968). A number of MS theses and doctoral dissertations have been defended at our cytology laboratories. The Section of Cytology (now Croatian Society of Clinical Cytologists, Croatian Medical Association) was founded in 1970, owing to the efforts invested by E. Hauptmann. Clinical cytologists from Merkur University Hospital contributed to the foundation of the Association of Clinical Cytologists of the then Yugoslavia and organized their first congress in 1979; in 1972, we were adopted members of the EFCS, while Z. Singer and I. Crepinko are IAC members. I wish that written memories help remember the foundation and development of clinical cytology at Merkur University Hospital because we should not forget that every future has its origin.