140 patients have been investigated by means of computerized tomography (CT) after contrast injection and radionuclide scan (RN scan). For patients with stroke (56 cases), RN uptake was more frequent (80%) at the 15th day of evolution, enhancement of hypodense images at CT reaches 100% at the 21st day. For the others pathologies (hematoma, tumors), the main difference between both examinations, was the volume of the lesions detected. RN uptake and CT enhancement both show the same blood brain barrier disturbance.