Purpose: To observe the quantity and activity of osteoclast in peri-implant tissues dynamically.
Methods: An animal model of dental implants was established in 6 male Beagle dogs of 1-2 years old. Bone remodeling was tested at 3-, 7-,15-,30-,60- and 90-day after placement of implants. The mandibular bones were taken out and the morphological changes were observed under X-ray examination.Bone tissue samples underwent HE staining. The data were analyzed with SPSS13.0 software package.
Results: The most prominent period of osteoclasts occurred at 7-day after placement of implants. After 7 days of implantation, the activity of osteoclast gradually decreased.
Conclusions: The active stage for bone remodelling in peri-implant tissues during unloading period is about 7 days after implantation.