Molecular characterization of methicillin-sensitive Staphylococcus aureus isolates from bacteremic patients in a Norwegian University Hospital

J Clin Microbiol. 2013 Jan;51(1):345-7. doi: 10.1128/JCM.02571-12. Epub 2012 Nov 7.

Abstract

Staphylococcus aureus bacteremia is common in both nosocomial and community settings, and the pathogenicity of the microbe depends upon a large repertoire of virulence factors. S. aureus bacteremia isolates (n = 126) were characterized using DNA microarrays. Clonal complexes 5, 8, 15, 30, and 45 accounted for 74.6% of the isolates. We identified geographical differences in dominating clones and toxin gene profiles. One isolate was methicillin resistant. Potential associations between age and genotype were detected.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Bacteremia / epidemiology*
  • Bacteremia / microbiology*
  • Child
  • Child, Preschool
  • Cluster Analysis
  • Female
  • Genes, Bacterial
  • Genotype
  • Hospitals, University
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Microarray Analysis
  • Middle Aged
  • Norway / epidemiology
  • Oligonucleotide Array Sequence Analysis
  • Phylogeography
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / classification
  • Staphylococcus aureus / genetics*
  • Staphylococcus aureus / isolation & purification*
  • Young Adult