Management of neck metastases in T2N0 lip squamous cell carcinoma

Am J Otolaryngol. 2013 Mar-Apr;34(2):103-6. doi: 10.1016/j.amjoto.2012.09.007. Epub 2012 Nov 17.

Abstract

Background: Prophylactic neck dissection (PND) is indicated when the chance of occult lymph node metastases from head and neck tumors is significant. There is no consensus regarding which tumor size PND would be indicated in cases of lip cancer.

Methods: A total of 139 patients with surgically treated lip cancer were selected. The size of the lesion (T) and the presence of lymph node metastases (N) were assessed by examining the medical records. For analysis purposes, the T2 group was divided into T2a (2 to 3 cm) and T2b (3 to 4 cm).

Results: The following distribution of incidence of neck metastases was observed in the study groups: 11.7% in T1, 9% in T2a, 43.7% in T2b, and 52.2% in T3+T4. Statistical comparison of the groups (p) revealed the following results: T2aXT2b=0.03; T2aXT3+T4=0.001.

Conclusion: PND is indicated for tumors larger than 3 cm.

MeSH terms

  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / secondary*
  • Carcinoma, Squamous Cell / surgery*
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / secondary*
  • Head and Neck Neoplasms / surgery*
  • Humans
  • Lip Neoplasms / pathology*
  • Lymph Node Excision*
  • Lymphatic Metastasis
  • Squamous Cell Carcinoma of Head and Neck