Abstract
We describe a 17-year-old patient presenting perimyocarditis as the initial manifestation of the adult-onset Still's disease. Corticotherapy was rapidly successful but induced major acute hepatitis in relation with Epstein-Barr virus reactivation. After 1 year, even if the global outcome is favourable, a slightly lowered ejection fraction still persists. Former case reports and differential diagnosis with reactive haemophagocytic syndrome would be discussed.
MeSH terms
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Adolescent
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Anti-Inflammatory Agents / adverse effects
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Anti-Inflammatory Agents / therapeutic use
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Chemical and Drug Induced Liver Injury / diagnosis
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Diagnosis, Differential
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Dose-Response Relationship, Drug
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Drug Administration Schedule
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Echocardiography
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Epstein-Barr Virus Infections / diagnosis*
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Heart Ventricles / pathology
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Humans
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Lymphohistiocytosis, Hemophagocytic / diagnosis
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Magnetic Resonance Imaging
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Male
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Myocarditis / diagnosis*
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Myocardium / pathology
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Pericarditis / diagnosis*
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Prednisone / adverse effects
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Prednisone / therapeutic use
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Still's Disease, Adult-Onset / diagnosis*
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Still's Disease, Adult-Onset / drug therapy
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Virus Activation*
Substances
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Anti-Inflammatory Agents
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Prednisone