A rural outbreak of Legionnaires' disease linked to visiting a retail store

Am J Public Health. 1990 Apr;80(4):431-4. doi: 10.2105/ajph.80.4.431.

Abstract

Between May 7 and June 7, 1986, 27 residents of a rural county in Maryland developed legionellosis, and two died. Legionella pneumophila serogroup 1 was cultured from the sputum of two patients and identified in lung tissue of a third patient by direct fluorescent antibody staining. An additional 11 patients had four-fold rises in antibody titer to L. pneumophila, and 13 had single titers greater than or equal to 1:256. To determine risk factors for disease, we performed a case-control study. Twelve of 16 case-patients reported visiting store A in the two weeks before onset of illness compared with four of 28 control-patients. A serologic survey of employees showed that employees of store A were 3.63 times more likely than control employees to have titers of antibody to L. pneumophila greater than or equal to 1:256 (95% confidence intervals 0.8, 16.7). Cultures of soil specimens, samples of water from the hot water system of store A and from stagnant ponds near store A collected five weeks after the end of the outbreak were negative for Legionella species. Store A was adjacent to a site of excavation and construction during May 1986, when the community was experiencing an extended drought. This investigation suggests that exposure to excavation and construction activity may be a risk factor for legionellosis.

MeSH terms

  • Adult
  • Aged
  • Antibodies, Bacterial / isolation & purification
  • Case-Control Studies
  • Disease Outbreaks*
  • Environmental Exposure*
  • Female
  • Humans
  • Legionella / immunology
  • Legionnaires' Disease / epidemiology*
  • Male
  • Maryland / epidemiology
  • Middle Aged
  • Rural Population*
  • Soil Microbiology
  • Water Microbiology

Substances

  • Antibodies, Bacterial