This article reviews the available evidence for the pharmacological treatment of three of the psychotic disorders that are groupped together with schizophrenia in its chapter; one of them chronic -though episodic in its course- (schizoaffective disorder), two of them with acute symptomatology and restitutio ad integrum (schizophreniform disorder, brief psychotic disorder). The controversial position of these disorders in psychiatric nosology explains the scarce evidence for their pharmacological treatment. Anyhow, we shall try to stablish the main therapeutical approaches to these disorders.