IDH1 and IDH2 mutations in therapy-related myelodysplastic syndrome and acute myeloid leukemia are associated with a normal karyotype and with der(1;7)(q10;p10)

Leukemia. 2013 Apr;27(4):957-9. doi: 10.1038/leu.2012.347. Epub 2012 Nov 29.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Chromosomes, Human, Pair 1*
  • Chromosomes, Human, Pair 7*
  • Female
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Karyotyping
  • Leukemia, Myeloid, Acute / genetics*
  • Male
  • Middle Aged
  • Mutation
  • Myelodysplastic Syndromes / chemically induced*
  • Myelodysplastic Syndromes / genetics
  • Translocation, Genetic

Substances

  • IDH2 protein, human
  • Isocitrate Dehydrogenase
  • IDH1 protein, human