Lumusidines A-D and villalstonidine F, macroline-macroline and macroline-pleiocarpamine bisindole alkaloids from Alstonia macrophylla

Phytochemistry. 2013 Mar:87:148-56. doi: 10.1016/j.phytochem.2012.11.005. Epub 2012 Nov 28.

Abstract

Lumusidines A-D, bisindole alkaloids of the macroline-macroline type, and one of the macroline-pleiocarpamine type, villalstonidine F, were isolated from the stem-bark extract of Alstonia macrophylla (Apocynaceae). The structures and absolute configurations of these alkaloids were established using NMR, MS, and X-ray diffraction analyses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry*
  • Alstonia / chemistry*
  • Indole Alkaloids / chemistry*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Oxindoles
  • Plant Extracts / chemistry*
  • X-Ray Diffraction

Substances

  • Alkaloids
  • Indole Alkaloids
  • Oxindoles
  • Plant Extracts
  • macroline
  • pleiocarpamine