Three cases of an unusual pattern of invasion in malignant Brenner tumors

Int J Gynecol Pathol. 2013 Jan;32(1):31-4. doi: 10.1097/PGP.0b013e318253c6cb.

Abstract

Ovarian malignant Brenner tumors are rare neoplasms that are typically admixed with benign and borderline Brenner tumor elements. We report 3 cases of an unusual variant of malignant Brenner tumor where the infiltrative malignant component arose directly from a benign Brenner tumor rather than from borderline elements and did not exhibit a desmoplastic stromal response. Borderline elements were present in 1 case, but the invasive component did not arise from these. Our cases highlight that an absence of a borderline element should not dissuade the pathologist from diagnosing a malignant Brenner tumor.

Publication types

  • Case Reports

MeSH terms

  • Brenner Tumor / pathology*
  • Female
  • Humans
  • Middle Aged
  • Ovarian Neoplasms / pathology*