Understanding the molecular sensitization for Cypress pollen and peach in the Languedoc-Roussillon area

Allergy. 2013 Feb;68(2):249-51. doi: 10.1111/all.12073. Epub 2012 Dec 4.

Abstract

Background: Cypress allergy is a typical winter pollinosis and the most frequent one in the South of France. Main symptoms are rhinitis, conjunctivitis, and asthma. Peach allergy is common too in Southern Europe. Allergic cross-reactions between cypress and peach have been reported, including an oral allergy syndrome. We wanted to investigate whether a cross-reactive allergen between cypress and peach might be responsible for the observed clinical association.

Methods: We analyzed 127 patients included over a 3-month period, outside the pollen season, and we dosed specific IgE levels, for selected, individual allergens.

Results: Patients sensitized to peach were mainly positive for the peach-nonspecific lipid-transfer protein.

Conclusions: Profilins or thaumatins could not explain the observed clinical association between cypress and peach.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Allergens*
  • Antigens, Plant / immunology
  • Asthma / diagnosis
  • Asthma / immunology
  • Cohort Studies
  • Cross Reactions / immunology*
  • Cupressus / immunology*
  • Female
  • France
  • Humans
  • Hypersensitivity / etiology*
  • Hypersensitivity / physiopathology
  • Immunization / methods*
  • Male
  • Middle Aged
  • Pollen / immunology
  • Prospective Studies
  • Prunus / immunology*
  • Rhinitis, Allergic, Seasonal / diagnosis
  • Rhinitis, Allergic, Seasonal / immunology
  • Risk Assessment
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Skin Tests / methods

Substances

  • Allergens
  • Antigens, Plant