Abstract
Nocardia concava was identified as a new species in 2005; however, the clinical manifestations of Nocardia concava infection have yet to be clarified. We herein present the case of an immunosuppressed patient who developed disseminated nocardiosis caused by N. concava with multiple abscesses in the lungs, cutis, subcutaneous tissue, skeletal muscles and kidneys accompanied by central nervous system involvement, including meningitis and ventriculitis. The patient was cured with appropriate treatment including linezolid after testing for susceptibility. Linezolid should be considered as an alternative agent for treating disseminated nocardiosis because of its effective distribution to multiple sites.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetamides / therapeutic use*
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Acute Disease
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Aged
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Anti-Bacterial Agents / therapeutic use*
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Central Nervous System Diseases / diagnosis
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Central Nervous System Diseases / drug therapy*
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Central Nervous System Diseases / microbiology
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Humans
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Immunocompromised Host
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Linezolid
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Male
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Microbial Sensitivity Tests
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Minocycline / therapeutic use
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Nocardia / classification
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Nocardia / drug effects
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Nocardia / genetics
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Nocardia Infections / diagnosis
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Nocardia Infections / drug therapy*
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Nocardia Infections / microbiology
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Oxazolidinones / therapeutic use*
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Respiratory Insufficiency / drug therapy*
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Respiratory Insufficiency / microbiology
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Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
Substances
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Acetamides
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Anti-Bacterial Agents
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Oxazolidinones
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Trimethoprim, Sulfamethoxazole Drug Combination
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Minocycline
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Linezolid