Abstract
The discovery of vitamins as essential factors in the diet was a scientific breakthrough that changed the world. Diseases such as scurvy, rickets, beriberi, and pellagra were recognized to be curable with an adequate diet. These diseases had been prevalent for thousands of years and had a dramatic impact on societies as well as on economic development. This Review highlights the key achievements in the development of industrial processes for the manufacture of eight of the 13 vitamins.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Historical Article
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Review
MeSH terms
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Ascorbic Acid / chemical synthesis
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Ascorbic Acid / history
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Ascorbic Acid / metabolism
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Biotin / chemical synthesis
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Biotin / history
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Biotin / metabolism
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History, 20th Century
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Humans
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Natural Science Disciplines / history*
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Pantothenic Acid / chemical synthesis
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Pantothenic Acid / history
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Pantothenic Acid / metabolism
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Pyridoxine / chemical synthesis
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Pyridoxine / history
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Pyridoxine / metabolism
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Riboflavin / chemical synthesis
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Riboflavin / history
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Riboflavin / metabolism
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Thiamine / chemical synthesis
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Thiamine / history
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Thiamine / metabolism
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Vitamin A / chemical synthesis
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Vitamin A / history
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Vitamin A / metabolism
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Vitamin E / chemical synthesis
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Vitamin E / history
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Vitamin E / metabolism
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Vitamins / chemical synthesis
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Vitamins / history*
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Vitamins / metabolism
Substances
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Vitamins
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Vitamin A
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Vitamin E
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Pantothenic Acid
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Biotin
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Pyridoxine
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Ascorbic Acid
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Riboflavin
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Thiamine