Abstract
One hundred and three patients treated with CAP chemotherapy were evaluated to determine the relationship between low prechemotherapy serum albumin (less than 3 g/dl) and low WBC nadir (less than 2000 cells/mm3). Additionally, the relationship of serum albumin to renal toxicity (delta serum creatinine) was examined. Low prechemotherapy serum albumin appears to be a marker for advanced disease, but does not appear to predict marrow or renal toxicity.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / adverse effects*
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Bone Marrow Diseases / blood
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Bone Marrow Diseases / chemically induced*
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Cisplatin / administration & dosage
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Creatinine / blood
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Cyclophosphamide / administration & dosage
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Doxorubicin / administration & dosage
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Female
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Humans
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Kidney Diseases / blood
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Kidney Diseases / chemically induced*
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Leukocyte Count / drug effects
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Middle Aged
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Neoplasm Staging
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Ovarian Neoplasms / drug therapy*
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Ovarian Neoplasms / mortality
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Ovarian Neoplasms / pathology
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Serum Albumin / metabolism*
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Survival Rate
Substances
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Serum Albumin
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Doxorubicin
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Cyclophosphamide
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Creatinine
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Cisplatin